Researchers have used MRI brain scans of children with isolated fetal ventriculomegaly to measure neurodevelopment and investigate the presence of autism traits at school age. In a paper published in the journal Nature Communications, King’s College London researchers from the Center for the Deve
Scientists used MRI scans of children with isolated fetal ventriculomegaly and found evidence supporting an association between the condition and autism traits. The study followed two groups of children, those with a normal fetal brain MR assessment and those with isolated ventriculomegaly, and conducted developmental assessments at ages 2 and primary school age. The results could improve family counseling, early identification, and intervention.
The study followed two groups of children, one with a normal fetal brain MR assessment and those with an antenatal diagnosis of isolated ventriculomegaly, with a developmental follow-up assessments at 2 years of age and primary school age. Fetal ventriculomegaly is the most common antenatally-diagnosed brain abnormality and is diagnosed when the lateral ventricles measure larger than normal on antenatal ultrasound or MR imaging.
“There is a clear need for more long-term data combining high quality brain imaging with long term developmental follow up in children with antenatally-diagnosed isolated ventriculomegaly or indeed with other common fetal brain anomalies to improve our understanding about the susceptibility of developing autism.
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