Popular weight loss drugs like Wegovy and Ozempic could increase the risk of stomach paralysis as well as several other serious gastrointestinal conditions, according to a study published in JAMA.
Popular weight loss drugs like Wegovy and Ozempic could increase the risk of stomach paralysis as well as several other serious gastrointestinal conditions, according to a study published Thursday in JAMA. This was the first large epidemiological study to examine these adverse effects in non-diabetic patients using the drugs specifically for weight loss, per a press release from The University of British Columbia .
Stomach paralysis, officially known as gastroparesis, prevents the nerves and muscles in the stomach from moving food into the small intestine, which keeps digestion from occurring, as described on Cleveland Clinic’s website. In addition to stomach paralysis, the drugs were linked to a greater risk of pancreatitis and bowel obstruction, which prevents food from passing through the small or large intestine, the release stated.
In August, a Louisiana woman sued Novo Nordisk, the manufacturer of Ozempic and Wegovy, and Lilly, which makes another GLP-1 agonist, Mounjaro, claiming that the companies 'downplayed the severity of gastrointestinal events caused by Ozempic and Mounjaro — never, for example, warning of the risk of gastroparesis or gastroenteritis.
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