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. The medication, which is indicated for the treatment of type 2 diabetes, is often prescribed off-label for weight loss—and while it's certainly effective, some patients have reported gastrointestinal issues and a slew of unpleasant complications. But although these side effects can be debilitating for some, there have also been reports of glucagon-like peptide-1 agonists—the class of medication Ozempic and its sister drug, Wegovy, fall under—changing patients' personalities..
It may also just be that the desires are subdued, as patients on Ozempic do still eat, just not as much as they did before they were on the medication. In terms of decreased libido or interest in having sex, Berridge offered an explanation for that, too. When the reward pathway for this is suppressed, patients might not be as interested in physical intimacy.
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