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This is the second study this fall to suggest that GLP-1s, such as Novo Nordisk’s Ozempic and Wegovy or
Patients with opioid-use disorder who used a GLP-1 drug had a 40% lower rate of opioid overdoses than those who did not, according to the study. That study, however, was limited solely to patients with Type 2 diabetes who had a prescription for Ozempic, whereas the study published this week examined patients on other GLP-1 drugs, including Wegovy, Zepbound, and Mounjaro. The results of both studies were limited because they involved medical record analysis, not randomized clinical trials, which would be necessary to determine how the drugs work to reduce overdose and intoxication rates.
In other words, GLP-1s may prevent people from overconsuming opioids and alcohol to the point of medical emergency but not actually help with quitting.There have been little changes in the use of medications to treat opioid or alcohol addictions in the 21st century.
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