Science, Space and Technology News 2024
Researchers at the University of Cambridge have discovered that regulatory T cells form a single, mobile population that patrols the entire body to repair tissue damage. This new understanding could revolutionize the treatment of various diseases by enabling targeted immune suppression and tissue regeneration in specific organs, potentially improving the effectiveness and speed of treatments. The team is now working towards clinical trials to further explore these findings.
Current anti-inflammatory drugs treat the whole body, rather than just the part needing treatment. The researchers say their findings mean it could be possible to shut down the body’s immune response and repair damage in any specific part of the body, without affecting the rest of it. This means that higher, more targeted doses of drugs could be used to treat disease – potentially with rapid results.
“It’s difficult to think of a disease, injury, or infection that doesn’t involve some kind of immune response, and our finding really changes the way we could control this response,” said Liston. Dr. Oliver Burton, lead author on the study, uses spectral cytometry to analyze anti-inflammatory regulatory T cells from different tissues. Credit: Louisa Wood, Babraham Institute
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