Results from the LAURA trial will change practice once its label gets expanded, experts said at the ASCO 2024 annual meeting.
may soon have approvals across all stages of epidermal growth factor receptor –mutated non–small cell lung cancer .annual meeting and funded by AstraZeneca, will likely lead to an approval for the remaining indication: Unresectable stage III disease.
Twelve-month progression-free survival, assessed by blinded independent central review, was 74% with osimertinib vs 22% with placebo. At 24 months, the rates were 65% and 13%, respectively. Based on these results,"osimertinib will become the new standard of care" after definitive chemoradiation in this patient population, Ramalingam said.
Sequist, who reported ties to AstraZeneca, noted that patients were treated with osimertinib until progression, not for a limited duration as in past EGFR TKI trials, raising the possibility of indefinite, life-long treatment.
Nsclc Lung Cancer Lung Carcinoma Cancer Of The Lung Secondary Malignant Neoplasm Of The Lung Secondary Malignant Lung Neoplasm Secondary Lung Cancer Metastatic Lung Cancer Lung Metastases Lung Metastasis Brain Metastasis Metastatic Brain Tumor Metastatic Disease To The Brain Brain Metastases Metastatic Brain Tumour Metastasis Metastatic Carcinoma
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