Oral vaccine shows promise; hypertension ups COVID hospitalization risk

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Oral vaccine shows promise; hypertension ups COVID hospitalization risk
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The following is a summary of some recent studies on COVID-19. They include research that warrants further study to corroborate the findings and that has yet to be certified by peer review.

High blood pressure more than doubles the risk of hospitalization during COVID-19 infections with the coronavirus Omicron variant, even in people who are fully vaccinated and boosted, a U.S. study showed.

Doctors at Cedars-Sinai Medical Center in Los Angeles studied 912 people with COVID-19 when Omicron was the dominant variant despite having received at least three doses of an mRNA vaccine from Pfizer/BioNTech or Moderna, including 145 who required hospitalization. The risk for severe disease was increased in people with well-known risk factors such as older age, heart failure or kidney disease, the researchers reported on Thursday in the journal.

"We were surprised to learn that many people who were hospitalized with COVID-19 had hypertension and no other risk factors," study leader Dr. Susan Cheng said in a statement. "This is concerning when you consider that almost half of American adults have high blood pressure."Infection with the Omicron variant of the coronavirus in the third trimester of pregnancy is linked with an increased risk of preterm delivery, according to Israeli researchers.

Doctors there compared 2,753 pregnant patients with positive PCR tests for the virus this year to the same number of similar but uninfected pregnant patients. Infections were not associated with preterm birth when diagnosed in the first or second trimester. But nearly half of the women were infected in the third trimester. In this group, rates of preterm birth were 5.8%, compared to 2.3% among uninfected women at the same stage of pregnancy, the study found.

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