Eli Lilly's efsitora alfa was noninferior to once-daily insulin in type 2 diabetes, but an increased hypoglycemia risk was seen in type 1 diabetes.
MADRID, Spain — Eli Lilly's investigational once-weekly basal insulin analog efsitora alfa continues to show noninferiority to once-daily insulin in people with
In a commentary during the EASD session, Cornelis J. Tack, professor of internal medicine and head of the diabetes section at Radboud University Medical College, Nijmegen, the Netherlands, called QWINT-2 and QWINT-5"high-quality clinical studies in relevant populations providing important scientific information. Once-weekly insulin efsitora performs equal to once-daily insulin in insulin-naive people with type 2 diabetes.
Rates of combined clinically significant and severe hypoglycemia were 0.58 vs 0.45 events per participant-year of exposure with efsitora and degludec, respectively, a nonsignificant difference. No severe hypoglycemia was reported with efsitora, whereas six episodes were reported with degludec. The incidence of other adverse events was similar in the two groups.
Diabetes Mellitus Type Ii Type 2 Diabetes Type 2 DM T2DM T2D Hypoglycemia Diabetes Mellitus Type 1 Diabetes Mellitus Type I Type 1 Diabetes Type 1 DM T1DM T1D Clinical Research Clinical Trials Clinical Studies Pre-Clinical Trial Double-Blind Study Double-Blind Studies Single-Blind Study Single-Blind Studies Healthcare And Medical Technology
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