The monoclonal antibody ofatumumab is more effective in achieving a disease-free state in RRMS than the immunomodulatory drug teriflunomide, results of a phase 3 trial suggested.
The monoclonal antibody ofatumumab appears to be more effective in achieving a disease-free state in relapsing-remitting multiple sclerosis than the immunomodulatory drug teriflunomide, across racial groups, show results of a randomized, double-blind clinical, phase 3 trial.Researchers conducted a post hoc analysis of the phase 3 ASCLEPIOS I and II trials to compare the efficacy and safety of ofatumumab and teriflunomide in diverse racial and ethnic subgroups of participants with RRMS.
Participants were randomized to receive ofatumumab 20 mg subcutaneously every 4 weeks or teriflunomide 14 mg orally once daily for up to 30 months.
Multiple Sclerosis MS - Multiple Sclerosis Monoclonal Antibody Cetuximab Rituximab Biologic Therapy Biologics Relapsing Remitting Multiple Sclerosis RRMS - Relapsing Remitting Multiple Sclerosis Relapsing Remitting MS
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