A new study finds the popular obesity drug Zepbound may help treat sleep apnea, a dangerous disorder in which people struggle to breathe during sleep.
FILE - A woman demonstrates how she puts on her sleep apnea breathing device at her home in Los Angeles Thursday, July 12, 2018. Tirzepatide, used to treat diabetes and obesity, can help with sleep apnea, a dangerous disorder in which people struggle to breathe while they sleep, according to a study, published Friday, June 21, 2024, in the New England Journal of Medicine,
The research, published Friday in the New England Journal of Medicine and presented at a medical meeting, included nearly 500 people diagnosed with obesity and sleep apnea. Half of them used what's typically known as a CPAP machine that feeds oxygen through a mask to keep airways open during sleep. The other group included people for whom a CPAP machine had failed or wasn't tolerated.
On average, patients who took tirzepatide also lost between 18% and 20% of their body weight and showed improvements in blood pressure and a condition in which blood oxygen drops during sleep. Patients also reported better sleep and fewer sleep disturbances, the study found. In an accompanying editorial, Dr. Sanjay Patel, a sleep medicine specialist at the University of Pittsburgh, cautioned that whether tirzepatide can treat sleep apnea in real-world patients “remains unclear” because of the way improvement is measured. He also noted that cost and access remain obstacles to using tirzepatide and that the addition of the drug as a treatment could exacerbate racial and other disparities in addressing sleep apnea.
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