Nature research paper: Nuclear-embedded mitochondrial DNA sequences in 66,083 human genomes
. Letter-value plots of sequencing depth of whole genome sequencing and mitochondrial genome sequencing from the rare disease genomes. The middle line represents the median . Each successive level outward contains half of the remaining data. The first two sections out from the centre line contain 50% of the data. The next two sections contain 25% of the data. This continues until at the outlier level. The outliers are plotted as diamonds..
1%; ultra-rare F = 0.1%) shown in red links. Ultra-rare mtDNA-mtDNA breakpoints , individuals carrying putative concatenated NUMTs and without putative concatenated NUMTs shown, separately. Variants observed in the individuals carrying putative concatenated NUMTs are mixed variants from both mtDNA sequence and NUMTs. The middle line represents the median . Each successive level outward contains half of the remaining data. The first two sections out from the centre line contain 50% of the data.
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