A new study shows that nuchal translucency screens can detect a wide range of genetic disorders at lower thresholds than previously thought. Fetuses with measurements as low as 2 mm showed an increased risk for chromosomal abnormalities.
A new study provides large-scale, population-level evidence that nuchal translucency screens detect a wide range of genetic disorders at thresholds lower than the level currently considered indicative.
Fetuses with 2.5-3 mm NT measurements were at a sixfold relative risk than the control group, while fetuses within the 2-2.5 range were a little over two times as likely to have an abnormality . ACOG also said that clinicians may choose to follow the Society for Maternal-Fetal Medicine or American Institute of Ultrasound in Medicine guidance.
Dussault said she recognized the need for more robust methodological approaches to studying NT. They used data from Canada's perinatal registry network and included pregnancies with an estimated delivery date over a 5-year period starting in 2016. The average maternal age at delivery was 31.5 years. Saitta said an NT result can help expectant parents make better decisions, such as delivering at a higher acuity intensive care unit for newborns.
Nuchal Translucency Genetic Disorders Thresholds Chromosomal Abnormalities Study
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