The individualized metabolic surgery score could help set realistic weight loss targets with semaglutide in patients with type 2 diabetes and obesity.
Patients with both type 2 diabetes and obesity, who have a lower diabetes severity, as characterized by the individualized metabolic surgery scoring system, achieve better weight loss outcomes with semaglutide.Prior studies indicate that semaglutide leads to inferior weight loss outcomes in patients with obesity who have T2D vs those without T2D ; however, no study has assessed semaglutide's weight loss effects as a function of T2D severity.
This retrospective cohort study of patients with obesity and T2D taking ≥ 1 mg of semaglutide investigated weight loss outcomes over 12 months based on IMS scores at baseline as well as changes in glycemic parameters.
Diabetes Mellitus Type Ii Type 2 Diabetes Type 2 DM T2DM T2D Weight Loss Obesity Obese Weight Management Metabolism Metabolic Surgery Blood Grant Minnesota
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