Heart injury biomarker may help COVID-19patients avoid hospitalization, new study shows univofstandrews PLOSONE
]. The results of this study strongly indicate that the true clinical utility of troponin in COVID-19 may rest on it being a good rule-out test on an individual patient diagnostic level. A negative troponin would eliminate the influence of acute cardiac pathologies and the heterogeneous effects of confounders on prognosis. As a biomarker, the high sensitivity cardiac troponin threshold of 14 ng/L used in this study was derived from the 99].
Although troponin assays were ordered at the discretion of the treating physician at the time, owing to the paucity of data on the use of troponins in COVID-19, the assay results would not have been systematically used to guide clinical decision making. Instead, this study provides a blueprint for the further validation of cardiac troponins in clinical practice.
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