Nonstimulants: A Better Option for ADHD?

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Nonstimulants: A Better Option for ADHD?
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Children and adults with ADHD show greater improvement in symptoms with viloxazine extended release compared with treatment with atomoxetine, new research suggests. PsychTwitter

By 2 weeks, 86% of patients taking viloxazine reported a positive response vs 14% when taking atomoxetine.

Almost all participants preferred viloxazine over atomoxetine and 85% were able to taper off stimulant treatment following stabilization on viloxazine. The findings could represent"a paradigm shift for the field" because"we always think of starting ADHD treatment with stimulants, but perhaps treatment with viloxazine could help patients to avoid stimulants entirely," he suggested., Greg Mattingly, MD, associate Clinical Professor, Washington University, St. Louis, Missouri, called it"a timely addition to the clinical literature where for the first time ever we have 2 non-stimulant options approved for adults with ADHD.

"Simply put, this real-world study of 50 clinic patients found that viloxazine ER had faster onset, was significantly more effective, and was preferred by 96% of patients as compared to atomoxetine," he said.

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