Non-Diabetic Use Of GLP-1 Drugs Like Ozempic For Weight Loss Affecting Retail Sizing Curves

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Non-Diabetic Use Of GLP-1 Drugs Like Ozempic For Weight Loss Affecting Retail Sizing Curves
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I've been a journalist for 30 years, as a senior editor at W magazine, and for the last 17 years, covering retail and real estate as a senior editor at WWD. I write about luxury boutiques, independent retailers, department stores, mass chains, and digitally native brands, and the force that's redefining the way we shop – Amazon.

Ozempic and Wegovy are having an unintended but not entirely unpredictable effect on the apparel industry. Impact Analytics, an AI-based planning and forecasting company, found that the GLP-1 drugs, which are typically prescribed for diabetes but are used by millions for weight loss , are driving down sizes in department and specialty stores. And the issue has implications all along the supply chain.

The Impact Analytics report connects the dots between Ozempic and Wegovy use and clothing sizes and cites the effect of diminishing clothing measurements on retail profit margins. Impact Analytics used data from flagships on Manhattan’s Upper East Side, which it identified as the epicenter of non-diabetic use of GLP-1 drugs. Agrawal predicted a 10% shift in the next five years to smaller sizes.“About 1.5 million Americans are going to get these drugs in the next five years,” Agrawal said. “That’s more than got them in 2023 and there are more new drugs coming.

Impact Analytics said size small has become the most popular size for women on the Upper East Side. Compared to 2022, sales of women’s button-down shirts in small sizes increased in 2024 by 12%, while sales of large sizes decreased by 10.9%.

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