This year’s Nobel Prize in physiology or medicine has been awarded to Katalin Karikó and Drew Weissman for their work on mRNA vaccines, which were crucial in curtailing the spread of COVID-19.
The Nobel Prize committee announced the prestigious honor, seen as the pinnacle of scientific achievement, in Sweden on Monday.It praised the scientists’ “groundbreaking findings,” which the committee said “fundamentally changed our understanding of how mRNA interacts with our immune system.
Karikó, a Hungarian-American biochemist, and Weissman, an American physician, are both professors at the University of Pennsylvania. Their work became the foundation for Pfizer and its German-based partner BioNTech, as well as Moderna, to use a new approach to produce vaccines that use messenger RNA or mRNA.
J. Larry Jameson, executive vice president of UPenn’s School of Medicine, praised the scientists’ work which “changed the world.” She applied to grant after grant, but a string of rejections meant that in 1995, she was demoted from her position at UPenn. She was also diagnosed with cancer at the same time.
Weissman told CNN that their technology is much more efficient than traditional methods of producing vaccines.
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