Given the high efficacy of fecal microbiota transplantation, adding bezlotoxumab may not provide further reduction in recurrence.
Although the combination of fecal microbiota transplantation with bezlotoxumab was well-tolerated in patients with inflammatory bowel disease and recurrentMETHODOLOGY:
All participants received a single colonoscopic FMT from a universal stool bank and were randomly assigned to receive a single bezlotoxumab infusion or placebo infusion before or at the time of the FMT. Although participants in the treatment arm had higher odds of CDI recurrence, the difference wasn't statistically significant.
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