Most transplanted hearts are from donors who are brain dead, but new research shows a different approach can be just as successful and boost the number of available organs
It's called donation after circulatory death, a method long used to recover kidneys and other organs but not more fragile hearts. Duke Health researchers said Wednesday that using those long-shunned hearts could allow possibly thousands more patients a chance at a lifesaving transplant — expanding the number of donor hearts by 30%.
In contrast, donation after circulatory death occurs when someone has a nonsurvivable brain injury but, because all brain function hasn’t yet ceased, the family decides to withdraw life support and the heart stops. That means organs go without oxygen for a while before they can be recovered — and surgeons, worried the heart would be damaged, left it behind.
Survival six months later was about the same –- 94% for the recipients of cardiac-death donations and 90% for those who got the usual hearts, the researchers reported in the New England Journal of Medicine. Researchers in Australia and the U.K. first began trying DCD heart transplants about seven years ago. Duke pioneered the U.S. experiments in late 2019, one of about 20 U.S. hospitals now offering this method. Last year, there were 345 such heart transplants in the U.S., and 227 so far this year, according to the United Network for Organ Sharing.
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