New therapies for a range of conditions are coming in 2022

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New therapies for a range of conditions are coming in 2022
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Recent headlines have focused on treatments and vaccines for covid-19. But giant strides are about to be made in haemophilia, while there will be a resurgence of interest in neurological disorders and progress on malaria

in medical research has lately been dominated by treatments and vaccines for covid-19. But research in other areas has continued, and is about to bear fruit. In 2022 giant strides will be made in treating haemophilia, and there will be a resurgence of interest in drugs for neurological disorders—and progress on malaria.

The correct genes for clotting factors are introduced into the body by a harmless virus, a similar trick to that employed by some covid-19 vaccines. Instead of carrying the genetic recipe for a spike protein, however, the virus carries the instructions for making the missing proteins.

New therapeutics for diseases of the brain are also worth watching in 2022. The granting—by American regulators—of approval for Aduhelm, an Alzheimer’s drug made by Biogen, a biotech firm, in 2021 has reinvigorated interest in therapies for dementia and other neurological disorders—even though some question the efficacy of the new treatment. Eli Lilly, a drugs giant, hopes to follow in 2022 with its own Alzheimer’s drug, donanemab, which also targets the amyloid proteins in the brain.

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