New Technology To Improve Cancer Detection and Treatment A new device can detect cancer cells without invasive and expensive surgery. Researchers from the University of Technology Sydney (UTS) have developed a new device that can detect and analyze cancer cells from blood samples, enabling docto
The Static Droplet Microfluidic device is able to rapidly detect circulating tumor cells that have broken away from a primary tumor and entered the bloodstream. Credit: Photo by Dr Majid WarkianiA new device can detect cancer cells without invasive and expensive surgery.
Professor Majid Warkiani from the UTS School of Biomedical Engineering said getting a biopsy can cause discomfort to patients, as well as an increased risk of complications due to surgery and higher costs, but an accurate cancer diagnosis is vital to effective treatment. The study, “Rapid metabolomic screening of cancer cells via high-throughput static droplet microfluidics,” has just been published in the peer-reviewed scientific journal,“In the 1920s, Otto Warburg discovered that cancer cells consume a lot of glucose and so produce more lactate. Our device monitors single cells for increased lactate using pH sensitive fluorescent dyes that detect acidification around cells,” said Professor Warkiani.
Circulating tumor cells are also precursors of metastasis – where cancer migrates to distant organs – which is the cause of 90% of cancer-associated deaths. Studying these cells may provide insights into the biology of cancer metastasis, which can inform the development of new treatments.
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