New Study Unveils Serotonin’s Key Role in Fertility and Depression

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New Study Unveils Serotonin’s Key Role in Fertility and Depression
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Scientists from Nagoya University in Japan have identified the role of serotonin neurons in linking glucose availability to reproductive health. Their research demonstrates how elevated glucose levels stimulate serotonergic neurons, leading to the release of serotonin, which in turn activates kisspeptin neurons responsible for reproductive hormone release.

Their findings indicate that serotonergic neurons can release serotonin when they sense high levels of glucose. By interacting with serotonin receptors in the kisspeptin neurons, they can improve reproductive functions. The use of inhibitors for serotonergic signaling also allowed the researchers to establish that the opposite was true. This important finding sheds light on why mammals with a poor diet face problems associated with fertility.

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