Scientists conclude that the virus that causes COVID-19, SARS-CoV-2, likely spilled from animals into people two separate times.
, which incorporated data collected by Chinese scientists, University of Arizona evolutionary biologist Michael Worobey and his colleagues used mapping tools to estimate the locations of more than 150 of the earliest reported COVID-19 cases from December 2019. They also mapped cases from January and February 2020 using data from a social media app that had created a channel for people with COVID-19 to get help.
They asked, “Of all the locations that the early cases could have lived, where did they live? And it turned out when we were able to look at this, there was this extraordinary pattern where the highest density of cases was both extremely near to and very centered on this market,” Worobey said at a press briefing.
Andersen said they found case clusters inside the market, too, “and that clustering is very, very specifically in the parts of the market" where they now know people were selling wildlife, such as raccoon dogs, that are susceptible to infection with the coronavirus., scientists analyzed the genomic diversity of the virus inside and outside of China starting with the earliest sample genomes in December 2019 and extending through mid-February 2020.
“Now I realize it sounds like I just said that a once-in-a-generation event happened twice in short succession,” Wertheim said. But certain conditions were in place — such as people and animals in close proximity and a virus that can spread from animals to people and from person to person. So “barriers to spillover have been lowered such that multiple introductions, we believe, should actually be expected,” he said.
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