Muscle injuries are common in the active population, and they cause the majority of player leaves in the world of sport. Depending on the severity, recovery of muscle function is quite slow and may require surgery, medication and rehabilitation.
Now, a study reveals a strategy to improve and accelerate recovery from muscle injuries that has potential application in the sports and health sector in general.
The new approach is important for the recovery of athletes -- especially in the competitive elite -- but also to mitigate the socio-economic impact of the loss of work productivity caused by these injuries on the active population.. The authors of the study are the experts Garoa Santoildes, Teresa Pagès, Joan Ramon Torrella and Ginés Viscor, from the Department of Cell Biology, Physiology and Immunology of the UB's Faculty of Biology.
Among other pathways, the HIF protein activates the proliferation of more capillary vessels through endothelial growth factor , a process that would bring more growth factors, metabolic substrates and oxygen to the muscle level to support the muscle regeneration process after injury. Therapy based on exposure to low concentrations of oxygen could also help to explore new treatments for pathophysiological injuries. Thus, it would be important to test whether hypoxia can counteract the muscle atrophy typical of sarcopenia -- a disease characterised by loss of muscle mass and strength -- through the processes involved in muscle recovery .
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