The study reveals the crucial role of Krause corpuscles, nerve cells in the penis and clitoris, in sexual responses and functions.
The research suggests that sexual reflexes are automatic, as genital reactions occurred even when the spinal cord’s connection to the brain was cut.
This discovery could pave the way for new treatments for conditions like erectile dysfunction and help restore sexual function in individuals with lower-body paralysis.Krause corpuscles, first discovered over 150 years ago, are similar in structure to touch-activated corpuscles found on fingers and hands. These corpuscles respond to vibrations as the skin moves across a textured surface.
To overcome this hurdle, Ginty and other sensory biologists utilized advanced molecular techniques to activate and track these neurons in mice. “Humans, it seems, realized that this was the best way to stimulate Krause corpuscles before any official experiments were published,” read the study. Activating these neurons in anesthetized mice triggered sexual reflexes in both male and female mice. Subsequently, the researchers discovered that the Krause corpuscles are connected to a specific area of the spinal cord.
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