Reproductive urologists from 14 major academic medical institutions have teamed up to combine data and conduct studies to increase treatment options for infertile men.
. They found that those with azoospermia rarely respond to the drug while those with baseline nonazoospermia, lower levels of, was conducted by researchers at Cleveland Clinic and the University of California Los Angeles. It is the first project of Male Organ Biology Yielding United Science , a new, multi-institutional research consortium seeking to better understand male infertility and expand treatment options. now includes investigators from 14 large US-based academic medical centers.
They noted that 1 in 6 couples will have difficulty conceiving a child, with male-factor infertility contributing to at least half of such cases.
Brannigan noted that for a large percentage of patients, clinicians cannot identify the root cause of their impaired reproductive potential. Some people may have a recognizable decline in semen parameters over time without clear lifestyle issues or clear hormonal imbalances or anatomical problems. Clinicians analyzed data from the questionnaires, which a team in Toronto collected and stored, in a series of studies, includingof fertility characteristics between men in the United States and Canada. Brannigan said MOBYUS is poised to produce a large dataset that can address retrospective questions and potentially prospectively collect data to answer prospective questions.
Lundy said MOBYUS' main goal is to identify a treatment that will change the avenue available for a couple to get pregnant. For example, he said, if a man has zero sperm in his semen, he often requires surgery to find and remove sperm from the testicle. If medications can produce low sperm counts, sperm found in the ejaculate can be frozen and surgery can be avoided.
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