Professor Jin-ho Chang's research team from the Department of Electrical Engineering and Computer Science at DGIST has developed 'Ultrasound-assisted photothermal therapy (ULTRA-PTT)' technology that significantly enhances the performance of conventional photothermal therapy. The findings of the study were published in Advanced Optical Materials.
New paradigm in photothermal therapy: Researchers develop ultrasound-assisted photothermal therapy technologyConceptual diagram of the ULTRA-PTT handpiece. The main parts of the ULTRA-PTT handpiece are the transparent housing, ultrasound transducer, optical module, and handpiece housing.
To address these issues, many researchers are conducting various studies, but the majority are focusing on developing"photothermal agents" that effectively absorb near-infrared laser wavelengths targeted at lesions. In contrast, research progress on methods to reduce optical scattering itself remains limited.
The"ULTRA-PTT handpiece" is designed for easy handling and comprises four components: the main body for user grip, the ultrasound generation unit that creates and maintains air bubbles within biological tissues, the laser irradiation unit that delivers light through a doughnut-shaped central hole on the main body, and the housing unit containing a medium for transmitting ultrasound to biological tissues.
Professor Chang of DGIST said,"This research allowed us to apply and expand the 'ultrasound-induced optical clearing' technology, which our team developed, to light-based therapy devices. Especially, the 'ULTRA-PTT handpiece' demonstrates excellent therapeutic performance in: New paradigm in photothermal therapy: Researchers develop ultrasound-assisted photothermal therapy technology retrieved 25 June 2024 from https://phys.
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