The single-tier test uses artificial intelligence to accurately detect Lyme disease from the first few weeks of infection through 1 year post-diagnosis.
A new blood test for Lyme disease outperforms standard diagnostic testing across all stages of the disease, according to new data presented at the 2025 Association for Diagnostics and Laboratory Medicine annual meeting in Chicago.
“If we could get a serology test that works better in early disease, that could have great benefits for both patients and providers,” Horn said.This new blood test, called LymeSeek, works differently by detecting 10 different antigens simultaneously. An algorithm developed using deep learning “sorts through all of the responses,” explained Holly Ahern, MS, MT, the chief scientific officer of ACES Diagnostics, the company developing LymeSeek, in Paradise Valley, Arizona.
In an additional analysis, the ACES diagnostics team also compared LymeSeek to STTT using samples from the Johns Hopkins Lyme Disease Research Center. In very early stages of disease , LymeSeek diagnosed 100% of Lyme cases, whereas standard testing identified only 37% of cases. In samples taken 3-4 weeks after EM appearance, LymeSeek’s results remained consistent, and standard testing identified 76% of cases.
Artificial Intelligence Deep Learning AI NPL Machine Learning ML Natural Language Processing Artificial Neural Networks Blood New York Serology Antigens Arizona Arthritis Joint Inflammation Borrelia Burgdorferi Clinical Research Clinical Trials Clinical Studies Pre-Clinical Trial Double-Blind Study Double-Blind Studies Single-Blind Study Single-Blind Studies
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