This 'smart insulin' is designed to stay inactive in the body until it’s needed and then activate instantly to manage blood sugar.
Scientists have created a groundbreaking type of insulin that adjusts to blood sugar levels in real-time, potentially transforming the treatment for millions of people with type 1 diabetes worldwide.
“While insulin has been saving lives for over 100 years now, and previous research has driven important changes for people with type 1, it is still not good enough – managing glucose levels with insulin is really tough, and it’s time for science to find ways to lift that burden,” said Rachel Connor, the director of research partnerships at JDRF UK, which is one of the entities behind this project.
The new glucose-responsive insulins are different. They activate only when blood sugar levels rise too high, preventing hyperglycemia, and deactivate when levels fall too low, avoiding hypoglycemia. In the future, patients might only need to take insulin once a week, according to experts.The scientists developing smart insulins have received millions in grants to accelerate their work.
“Even with the currently available modern insulins, people living with type 1 diabetes have to put lots of effort into managing their diabetes every day to find a good balance between acceptable glycemic control on the one hand and avoiding hypoglycemia on the other.”
Insulin Pancreas Type 1 Diabetes
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