'Breakthrough' results in mice could lead to the long-promised contraceptive pill for men.
Researchers at Baylor College of Medicine, Houston, developed a contraceptive that was 100% effective at reducing fertility in male mice after 21 days. And its effects were reversible. The drug targets a protein that's involved in normal sperm production and fertility in both mice and men.
"It's not something that's going to result in a product in the next 5 years," Nickels said."But it's something that 10 years down the line could be another method in a method mix that men are looking for."from Contraline that blocks the vas deferens and lasts about 2 years. The only approved forms of male birth control for men are condoms and vasectomies.
The research team treated mice with CDD-2807 and found that it could pass through the blood-testis barrier, but very little crossed the blood-brain barrier, Matzuk said —"one of the most fascinating findings of the work." It also did not show signs of toxicity. After 21 days of treatment, they tested the effects and found that none of the mice were able to impregnate female mice.
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