Laura is a science news writer, covering a wide variety of subjects, but she is particularly fascinated by all things aquatic, paleontology, nanotechnology, and exploring how science influences daily life. Laura is a proud former resident of the New Jersey shore, a competitive swimmer, and a fierce defender of the Oxford comma.
ArticleBody:Black widow spiders are among the world’s most venomous spiders, with a toxin that attacks the nervous system. While their bites can be treated with an antidote derived from other animals, a treatment that fully comes from human antibodies would ultimately be safer to use. A team in Germany is now closer to developing this kind of treatment. The potential therapeutic is described in a study published June 12 in the journal Frontiers in Immunology.
The currently available antivenom is also an undefined mix of antibodies that can vary from batch to batch, but is still the most efficient treatment option. To fix this, the team on this study set out to replace the formula with horse antibodies with recombinant human antibodies. They used an in vitro method called antibody phage display. “This approach uses extremely diverse gene collections of more than 10 billion different antibodies.
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