Statins lower the risk of dementia, however, a new drug negatively affects lung function. One of the most extensive global studies on the effects of cholesterol-lowering drugs has underscored a problem with a new class of drugs that could impair lung function in some patients. That’s the finding
A recent study, analyzing genetic data from 340,000 UK Biobank participants, has found that PCSK9 inhibitors, a new class of cholesterol-lowering drugs, could potentially impair lung function.
Genetic variants reflecting another cholesterol-lowering medication, statins, were found to correlate with higher BMI and body fat, as well as reduced testosterone. Statins are the most common cholesterol-lowering medication prescribed. “Our study reveals associations with lung function and brain size, which may influence how these drugs are prescribed or repurposed in the future,” Pham says. “These findings help us to understand how people may react to different drugs and assess the viability of new drug pathways.”
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