New Alzheimer's drug slows disease by a third

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New Alzheimer's drug slows disease by a third
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The second such drug in a year raises hopes we can start treating dementia.

We could be entering the era of Alzheimer's treatments, after the second drug in under a year has been shown to slow the disease.

Amyloid builds up in the spaces between brain cells, forming distinctive plaques that are one of the hallmarks of Alzheimer's. The full details of Eli Lilly's trial have yet to be published - but it has revealed the key findings:Donanemab was given as a monthly infusion until the distinctive plaques in the brain were gone

"We are encouraged by the potential clinical benefits that donanemab may provide, although like many effective treatments for debilitating and fatal diseases, there are associated risks that may be serious and life-threatening," Eli Lilly group vice-president of neuroscience research and development Dr Mark Mintun said.

"This should dispel any lingering doubts about this approach," Prof John Hardy, from the UK Dementia Research Institute, whose work led to the idea of targeting amyloid, 30 years ago, said. "Having two drugs is great for competition."

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