A case series characterized wounds associated with xylazine exposure, an increasingly common adulterant found in illicitly manufactured fentanyl in the United States.
A case series highlights the features of severe, necrotic skin wounds among hospitalized adults associated with xylazine exposure, including 9% that involved exposed deep structures such as bone or tendon.The alpha-2 agonist xylazine, a veterinary sedative, is increasingly detected in fentanyl used illicitly in the United States and may be causing necrotizing wounds in drug users.
To characterize specific clinical features of xylazine-associated wounds, researchers conducted a case series at three academic medical hospitals in Philadelphia from April 2022 to February 2023. They included 29 patients with confirmed xylazine exposure and a chief complaint that was wound-related, seen as inpatients or in the emergency department.The 29 patients had a total of 59 wounds, 90% were located on the arms and legs, and 69% were on the posterior upper or anterior lower extremities. Five wounds involved exposed deep structures such as the bone or tendon.
Of the 57 wounds with available photographs, 60% had wound beds with predominantly devitalized tissue , 11% were blisters, 9% had granulation tissue, and 21% had mixed tissue or other types of wound beds. Devitalized tissue was more commonly observed in medium or large wounds and 29% were chronic . Subacute and chronic wounds were often medium or large compared with acute wounds (OR, 48.
This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.
Wound Care Wound Necrotic Wound Tissue Bones Tendons Addiction Drug Abuse
United States Latest News, United States Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
Suspect in Houston fentanyl death arrested, sold 105 grams of fentanyl after victim's overdoseThe man linked to the fentanyl overdose death of a Houston man has been arrested and charged, according to U.S. Attorney's Office.
Read more »
Fentanyl crisis in Northeast Ohio: Leader of recovery center loses brother to fentanyl pills overdoseEven if you try other drugs and try to stay away from opioids, there’s a good chance you’ll get something with fentanyl mixed in it.
Read more »
Camp Hope helps heal the invisible wounds of warCamp Hope offers help and healing to veterans dealing with combat-related PTSD.
Read more »
Children brought from Gaza to heal from war wounds become caught in another war, in LebanonSeven-year-old Halima Abou Yassine was brought to Lebanon from Gaza for treatment after an Israeli strike left her near death with a gaping wound in her skull. She's one of a dozen Palestinian children from Gaza being treated in Lebanon under a program set up by a British-Palestinian surgeon, Dr. Ghassan Abu Sitta.
Read more »
Fentanyl in schools; Narcan incidents down 75% at Cleveland ISDOur investigation began in September 2023 when videos of drug overdoses on campus during the school day began circulating.
Read more »
Photos: California K-9 Sniffs Out 2.2 Pounds of Suspected Fentanyl Hidden in CarSource of breaking news and analysis, insightful commentary and original reporting, curated and written specifically for the new generation of independent and conservative thinkers.
Read more »