⭐️Our October issue is now live!⭐️ Featuring the Burden of Proof studies, how microbiome derived alcohol contributes to liver disease, new therapy trials for diabetes and obesity, wastewater surveillance in publichealth, and much more!
Serial heart MRI scans conducted in previously well people with mild initial COVID-19 illness suggest that lingering cardiac symptoms may be explained, at least in part, by ongoing mild cardiac inflammation.Trogocytosis-mediated tumor relapse after CAR-NK cell therapy prevented by inhibitory CARs
CAR-mediated trogocytosis contributes to dysfunction of natural killer cells by promoting fratricide and is an important mechanism of relapse after CAR-NK cell therapy. This problem can be overcome using a dual-CAR strategy that incorporates a dominant-negative signal to prevent NK cell fratricide and exhaustion, while sparing the CAR-activating signal against tumor targets.
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Health effects associated with vegetable consumption: a Burden of Proof study - Nature MedicineA meta-analysis using the Burden of Proof function identified modest evidence supporting a protective role of vegetable consumption and ischemicheartdisease, stroke and esophageal cancer, but not type 2 diabetes. IHME_UW
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Health effects associated with smoking: a Burden of Proof study - Nature MedicineA meta-analysis using the Burden of Proof method reported consistent evidence supporting harmful associations between smoking and 28 different health outcomes. IHME_UW
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Health effects associated with consumption of unprocessed red meat: a Burden of Proof study - Nature MedicineUsing the Burden of Proof analytical tool, a meta-analysis found weak or no evidence of associations between unprocessed redmeat consumption and increased risk of six cardiometabolic disease and cancer outcomes. IHME_UW
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Downsides of Proof-of-Work and Proof-of-Stake, explainedNot all consensus mechanisms are born equal — and the differences between major blockchains can have a huge effect on gas fees and transaction speeds.
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Shining a light on the psychological burden of cancer - Nature MedicineTo raise awareness of WorldMentalHealthDay here is the accompanying News and Views article highlighting the psychological burden of cancer WMHDay
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More frequent Chinese patrols put 'heavy burden' on aging Taiwan frigatesThe stepped up intensity of Chinese naval patrols near Taiwan since August is putting a 'heavy burden' on the island's aging frigate fleet, which is struggling to maintain combat readiness, the Taiwanese defence ministry said on Tuesday.
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