Interim analysis of first MIDAS trial findings showed 'highest rate of response and MRD negativity to date.'
shows a notably high response, with a favorable safety profile, according to the first findings of the ongoing, novel MIDAS trial.
In reporting on the initial findings from the induction phase of the phase 3 IFM 2020-02 MIDAS study, Perrot described results among 791 transplant-eligible patients with newly diagnosed MM and a median age of 59 who were enrolled at 72 centers between December 2021 and July 2023. In the intent-to-treat population, a very good partial response or better was achieved in 92% of patients following induction, with a rate of 99% in the per-protocol population.The rates of near-complete response and complete response were 64% and 66% in the ITT population, and 69% and 71% in the PP population.
"To have a large trial algorithm that is based on response and in particular MRD is novel and reflects the power of MRD in myeloma," said Mikhael, a professor of applied cancer research and drug discovery at the Translational Genomics Research Institute, City of Hope Cancer Center, in Phoenix.
Myeloma Plasma Cell Myeloma Biologic Therapy Biologics Transplantation Of Stem Cells Transplantation Of Hematopoietic Stem Cells Hematopoietic Stem Cell Transplant Stem Cell Transplantation Stem Cell Therapy Stem Cell Haematopoietic Stem Cell Transplant HSCT Hematopoietic Stem Cell Transplantation (HSCT) Haematopoietic Stem Cell Transplantation (HSCT)
United States Latest News, United States Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
Myeloma: Adding Daratumumab to Maintenance Therapy Improves MRD OutcomesAdding daratumumab to lenalidomide in maintenance therapy for multiple myeloma significantly reduced rates of minimal residual disease.
Read more »
Patti Scialfa, Bruce Springsteen's Wife, Reveals Multiple Myeloma DiagnosisPatti Scialfa, the wife of musician Bruce Springsteen and a member of his band the E Street Band, has publicly shared her diagnosis of multiple myeloma, a type of blood cancer. She revealed this information in the documentary 'Road Diary: Bruce Springsteen and the E Street Band,' which premiered at the Toronto Film Festival.
Read more »
Moving mountains: Boulder woman's battle against multiple myeloma during Blood Cancer Awareness MonthMaggy Wolanske is a multimedia journalist with Denver7.
Read more »
Multiple myeloma, explained: Patti Scialfa, Bruce Springsteen's wife and bandmate, reveals diagnosisAria Bendix is the breaking health reporter for NBC News Digital.
Read more »
Patti Scialfa, Bruce Springsteen's Wife, Has Multiple MyelomaHealth Reporter/Editor
Read more »
Patti Scialfa Reveals Multiple Myeloma DiagnosisPatti Scialfa, wife of Bruce Springsteen and member of the E Street Band, disclosed her diagnosis of multiple myeloma in a new documentary. Scialfa shared that she was diagnosed in 2018 and has been managing her condition carefully.
Read more »