One quarter of people are still infectious seven days after symptoms begin, and lateral flow tests are less accurate at the beginning of the illness than at the end
are still infectious five days after their symptoms begin, according to the most comprehensive study yet of people catching the virus in real life.– also called rapid antigen tests – give incorrect negative results about a third of the time when people are in the first days of developing covid-19, although they are much more accurate for detecting when people stop being infectious at the end of their illness.
Of more than 700 contacts of cases, 42 people had the beginning and end of their infectious period revealed by the tests. “We captured the moment they developed infection until they ceased to be infectious,” says Hakki. About one in five of these people were found to be infectious, according to the viral load assay, before any symptoms began. Lateral flow tests gave an accurate positive result 67 per cent of the time early on in the illness. Negative lateral flow results shouldn’t be trusted if people have symptoms, says Hakki.
Towards the end of people’s illness, two-thirds were still infectious five days after their symptoms began, although they did have lower levels of infectious virus in their nasal and throat mucus. A quarter were still infectious after seven days. In later stages of the illness as people’s viral loads fell, lateral flow tests correctly gave positive results for 92 per cent of people who were infectious.
“This shows beyond a shadow of a doubt that people are releasing infectious virus for far longer than is stated on current guidance,” saysHowever, the results may be slightly different for the
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