Most detailed human brain map ever contains 3,300 cell types

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Most detailed human brain map ever contains 3,300 cell types
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Nicoletta Lanese is the health channel editor at Live Science and was previously a news editor and staff writer at the site. She holds a graduate certificate in science communication from UC Santa Cruz and degrees in neuroscience and dance from the University of Florida.

It details the arrangement and inner workings of 3,300 types of brain cells, only a fraction of which were previously known to science. The research was released Thursday in the form of 21 new papers published across three journals: Science, Science Advances and Science Translational Medicine.

The research was conducted as part of a National Institutes of Health project known as the Brain Research through Advancing Innovative Neurotechnologies Initiative Cell Census Network, or BICCN. Launched in 2017, the massive project aims to catalog the cells found in the brains of mice, humans and nonhuman primates such as monkeys.

The BICCN human brain atlas used cutting-edge techniques that had previously mostly been used in animals, Mattia Maroso, a senior editor for the journal Science, wrote in the special issue published Thursday. Combining these techniques, researchers created single-cell-scale maps of the developing and adult human brain, as well as the brains of primates called marmosets and macaques . Some studies also looked at the brains of chimpanzees and gorillas .

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