More Than 180 Scientists Are Demanding That The Team Behind A Massive Hydroxychloroquine Study Share Their Data
of this and a related drug, chloroquine, warning that the drugs not be used outside of a hospital setting. For the first time, the Lancet study also found a link with a higher rate of deaths, finding that hospitalized patients who were given hydroxychloroquine were at least 33% more likely to die than those who did not receive the treatment.
In the wake of the Lancet study, two major hydroxychloroquine clinical trials — one by the World Health Organization, another in the United Kingdom —. And the governments of France, Belgium, and Italy banned the drug from being used as a coronavirus treatment. “Everything points to a drug that has no efficacy,” said Eric Topol, a cardiologist at the Scripps Research Translational Institute who hasn’t signed the letter but has expressed public skepticism about the use of hydroxychloroquine as a treatment. “There’s no sign that it helps anyone. We know it has significant side effects that are worrisome,” including cardiac arrest and a dangerously rapid heart rate called ventricular tachycardia.One of the letter signatories’ biggest concerns was that the authors had not released their code or data, even though the Lancet has“Many of us in the scientific community were just very angry at seeing a poorly written and executed study published in The Lancet, given loads of publicity, and then having a hugely negative impact on carefully planned clinical trials around the world,” said James Watson, a Thailand–based statistician with the University of Oxford’s Centre for Tropical Medicine and Global Health who led the drafting of the letter, by email to BuzzFeed News. According to the Lancet study, the patient data came from electronic health records, supply chain databases, and financial records. It was collected by Surgisphere, a Chicago-based health data-analytics company led by Sapan Desai, one of the study’s co-authors.
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