A recent approval and more products in the pipeline offer new treatment options.
New biologic drugs for chronic obstructive pulmonary disease are finally here, said Stephen Rennard, MD, in a presentation in a session on new drugs at the 2024 GOLD International COPD Conference.
Bafadhel, who served as one of the investigators on the BOREAS and NOTUS studies, explained some of the science behind the development of the new biologics. Understanding the mechanisms of the eosinophil in COPD is important for research and development, Bafadhel said. Along with standardizing measurement of T2 inflammatory markers , more research is needed to fully understand the role of eosinophils in immunoregulation and repair, she noted.
Itepekimab, another biologic, showed promise in a phase 2a genetic association study involving current and former smokers with moderate to severe COPD, Singh said., itepekimab failed to meet the primary endpoint in the overall study population of reduced annualized rate of moderate to severe exacerbations; however, a subgroup analysis of former smokers showed a significant reduction in exacerbations, Singh said in his presentation.
Newer biologic therapies in development are also injectables, but some studies are examining longer time intervals as long as every 6 months, which could be a major advancement for some patients, Mannino told. The newer therapies in development are similar to dupilumab in that they will be injected therapies. Some in development are looking at longer time intervals as long as every 6 months, which may be a major advancement for some patients, said Mannino.
COPD Chronic Obstructive Lung Disease COAD Chronic Obstructive Airway Disease (COAD) Chronic Obstructive Pulmonary Disease (COPD) Eosinophils Eosinophil Granulocytes Biologic Therapy Biologics U.S. Food And Drug Administration United States Food And Drug Administration FDA Food And Drug Administration (FDA) Food And Drug Administration Blood
United States Latest News, United States Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
BREAKING: Juan Soto signing with Mets on record-breaking $765 million contractJuan Soto is packing his bags and jumping across the Big Apple from the Bronx to Queens, where an awful lot of luggage will be needed if he has to haul the
Read more »
N.J. weather: Record-breaking rainless streak ends, but dry trend may start againAfter finally getting some light rain overnight, the Garden State region might go another week with no rain, forecasters say.
Read more »
Insider: Tesla Is Breaking Tons of Rules Elon Musk May Slash Under Trump“Tesla repeatedly asked me to lie to the government so that they could operate without paying for proper environmental controls,” a whistleblower reportedly wrote to the EPA.
Read more »
Pierce the Veil’s ‘I Can’t Hear You’ tour includes two stops in Pa.: Where to buy ticketsThe band will perform on May 19 in Philadelphia and on May 25 in Burgettstown.
Read more »
Pearl Jam’s newly announced 2025 tour dates include two shows in Pa.: Where to buy ticketsPearl Jam will perform on May 16 and May 18 at PPG Paints Arena in Pittsburgh.
Read more »
Kelly Ripa Turns Thanksgiving Dish Into Online StirYou may or may not agree on the name of this holiday side dish.
Read more »