Monkeypox Likely Circulated for Years Before Outbreak, Scientists Say

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Monkeypox Likely Circulated for Years Before Outbreak, Scientists Say
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For more than half a century, monkeypox was a rare infectious disease confined to one region of the world. At some point in the past few years, monkeypox jumped from an animal to a person and then kept spreading, infectious-disease experts believe.

Genetic mutations suggest current outbreak can be traced to animal-to-human infection from April 2016, according to one analysis

U.S. health officials have declared monkeypox a public-health emergency, after the World Health Organization declared it a global health emergency in late July. WSJ explains what you should look out for and what scientists know about how the virus is spreading. Illustration: Adele Morganconfined to one region of the world. A few months ago, that suddenly changed. Scientists are building a picture of what happened.

The explosion of monkeypox around the world is a case study in how infectious diseases can leap from limited circulation to wide geographic spread with just a few chance events. Infectious-disease experts knew that

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