FRIDAY, Oct. 13, 2023 (HealthDay News) -- Two years after a gene-edited pig kidney was transplanted into a monkey, researchers report the monkey is still alive.
“We’re the only group in the field to comprehensively address safety and efficacy of our donor organ with these edits,” said study co-author Dr. Mike Curtis, president and CEO of eGenesis, a company working on innovation in the field of organ transplantation.
Organ transplant has always involved the recipient having to take drugs to suppress their immune system and prevent rejection. One of the gene modifications knocked out part of the genes that make glycol antigens, structures made of sugar molecules that can trigger kidney rejection from the recipient, CNN reported.
The monkeys then lived for various lengths of time. They lived 50 days or fewer in those without the full edits. Among those who received the full edits, five lived for more than a year. One lived for two years.More from this section Treatment for Common Rotator Cuff Ailment May Be Useless Renters May Age Faster Than Homeowners, Study Finds Olympic Legend Mary Lou Retton Battling Rare Form of Pneumonia These aren’t the first pig organs used in research meant to save humans.
In that case, doctors removed the organ after two months, as planned, but it functioned the entire time. It was the longest documented case of a transplant between two species of its kind, CNN reported.
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