The use of Mohs surgery may improve survival for patients with early-stage Merkel cell carcinoma, results from a large, retrospective study show. ACMS2023 MCC
SEATTLE ― The use of Mohs surgery may improve survival for patients with early-stage Merkel cell carcinoma , results from a large, retrospective study show.
Although it's considered to be a rare cancer, the incidence of MCC has been rapidly rising, and in fact it doubled during the period from the 1990s to the 2010s. A growing body of literature supports Mohs surgery for many types of rare tumors, including MCC. For example, as, one study found that Mohs surgery compared favorably with the standard treatment approach when it came to recurrence rates for patients with MCC. The 5-year disease-specific survival rate was 91.2% for patients with stage I disease and 68.6% for patients with stage IIa.
The unadjusted 3-, 5-, and 10-year survival rates for patients treated with Mohs was 87.4% , 84.5% , and 81.8% , respectively, while for wide lesion excision, the rates were 86.1% , 76.9% , and 60.9% , respectively, "This study has important implications going forward," Cheraghlou concluded."We think it's important how few patients were treated with Mohs for Merkel cell, and it was slightly more likely to happen in a high-volume center."
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