Moderna would seek limited emergency use of COVID-19 vaccine based on early data

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Moderna would seek limited emergency use of COVID-19 vaccine based on early data
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If Moderna Inc's COVID-19 vaccine proves to be at least 70 percent effective, the company plans to seek emergency authorization for its use in high-risk groups, the company's chief executive told Reuters.

CHICAGO - If Moderna Inc’s COVID-19 vaccine proves to be at least 70 percent effective, the company plans to seek emergency authorization for its use in high-risk groups, the company’s chief executive told Reuters.

Vaccines must demonstrate they are at least 50% moreeffective than a placebo to be considered for approval. To provethat, government officials have said, at least 150 COVID-19infections must be recorded among trial participants with atleast twice as many occurring among the placebo group. If a vaccine is especially effective, companies could havetheir answer sooner.

“If the interim readout is deemed by the independent safety committee as positive with 70 or 80 or 90% efficacy, we will indeed consider approval,” Stephane Bancel, Moderna’s chief executive officer, said in a telephone interview. The two groups of high-risk individuals who might be covered in such an EUA would be healthcare workers and the elderly, Bancel said.

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