Moderna's Norovirus Vaccine Trial Shows Promise

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Moderna's Norovirus Vaccine Trial Shows Promise
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Moderna is testing a norovirus vaccine in a phase three trial with results expected as soon as this year. The trial is enrolling ahead of schedule, driven by a spike in norovirus cases this winter. While the vaccine targets specific norovirus genotypes, researchers hope it may offer broader protection. Moderna aims to reduce the severity of norovirus illness and prevent complications, particularly in vulnerable populations like seniors.

Moderna is testing a norovirus vaccine in a phase three trial, with results available as soon as this year.

"I don't know if it's directly attributable to the increased incidence of norovirus this season, but we clearly have a lot of interest in participation in this trial," Fink said. Moderna's vaccine candidate targets the three genotypes that the company says typically cause most infections. It works by showing the immune system something that looks like norovirus but isn't infectious, so the body can learn how to fight back if the real thing hits.

The company sees the main opportunity in vaccinating seniors who are particularly vulnerable to norovirus complications like dehydration. People 65 and up make up the majority of the estimated 900 Americans who die from norovirus complications in the U.S., according to the CDC.

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