The reformulated booster targets the BA.5 omicron subvariant, currently dominant in the U.S. The Biden administration plans to roll out the shots in the fall.
Moderna’s FDA application included data on another version of its vaccine that was designed to target both the original omicron variant, called BA.1, and the original coronavirus strain.that that new booster triggered an increase in antibodies against BA.4 and BA.5 in previously vaccinated and infected individuals, though the immune response was not as strong as the one generated against BA.1.
Moderna’s application also includes data on how well the BA.4/BA.5 booster shot performed in animal studies, as studies in humans have yet to be completed.controversial by some scientists , who say it remains unclear whether the new Covid shots will perform any better than the existing vaccines. "I think there is a serious risk now that the public could believe that the omicron-including boosters are going to be some kind of magic bullet," said John Moore, a professor of microbiology and immunology at Weill Cornell Medical College., is similar to how scientists select and test what strain or strains should be included in the flu shots each year.
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