Microwave-sized device outperforms dogs in sniffing out fentanyl at US border

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Microwave-sized device outperforms dogs in sniffing out fentanyl at US border
BayspecDrug ScreeningExplosives Detection
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Fentanyl-sniffing sensor outperforms dogs at border, detecting airborne drugs in seconds with pinpoint accuracy.

A portable device that sniffs out fentanyl, cocaine, and explosives from the air better than trained dogs could soon change how US border agents detect narcotics and other harmful substances.Named VaporID, the microwave oven–sized sensor was created at the Department of Energy’s Pacific Northwest National Laboratory and is being commercialized by California instrument maker BaySpec.

Unveiled at the American Society for Mass Spectrometry meeting in June, the system spots fentanyl vapour at six parts per trillion, far surpassing the five‑ to thirty‑minute turnaround of current swab tests. That’s sensitive enough to detect even the faintest trace of the substance.Finding the invisible trailA bench‑top version still in the lab reached ten parts per quadrillion, thanks to an atmospheric flow tube that gives scarce drug molecules extra time to bond with charged ions before identification.That’s like finding a single pine needle among all the trees in Washington, or spotting one coin in a stack of pennies reaching 17 million times the height of Mount Everest.In last year’s field trial at the Nogales, Arizona, border crossing, the device flagged trace fentanyl in seconds, along with methamphetamine, MDMA, cocaine, and ketamine, inside a Customs and Border Protection laboratory.Weighing 40 pounds, the unit draws in ambient air, steering suspect molecules into a miniature mass spectrometer for instant analysis. It can also sniff out fentanyl analogs, the chemically altered versions of the drug designed in illicit labs to evade detection.Dogs, data, and detectionCurrently, fentanyl is detected through contact sampling, which includes swiping surfaces for chemical analysis, or with the help of trained detection dogs. Border agents also rely on behavioral cues and other indicators to identify potential threats.PNNL has been working with BaySpec for the past two years to get the system ready for real-world use.A commercial version that can detect both narcotics and explosives is expected to roll out later this year.The team is also collaborating with the Department of Homeland Security to adapt the technology for screening cargo, baggage, mail, and people.The technology builds on more than a decade of research at PNNL on vapor detection for homeland security applications, including early work funded by the Defense Threat Reduction Agency.Detecting drugs like fentanyl or explosives such as TNT and PETN isn’t easy. These materials have low vapor pressure, meaning they release very few molecules into the air. Catching those rare molecules is even harder in busy settings filled with competing vapors from perfumes, fuels, and cleaners.The system filters out the background noise to focus on molecules of interest. It then tags them with ions, the electrically charged particles that act like gatekeepers, allowing only the targets through to the mass spectrometer for identification.A key feature is the atmospheric flow tube developed by PNNL chemist Robert Ewing and his team. It gives fentanyl molecules a few extra seconds to react with ions, increasing the chances of capturing even the faintest traces.

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