Today's Video Headlines: 11/14/25
That’s noteworthy, since traditional antidepressants can be slow to work, cause side effects and fail to help many patients.The disorder causes persistent sadness and a loss of interest in almost every part of life, affecting how people think, feel and behave — and often making work, school and relationships a struggle.
This is the age when cancer rates level off and actually dropCurious if this could help people with major depressive disorder, researchers at the University of Auckland in New Zealand recruited 19 volunteers to study the effects of microdosing LSD. Most participants were men, with an average age of 41, and 15 were already taking antidepressants when the study began. The volunteers were asked to take 16 doses of LSD under their tongues over an eight week period. They started with 8 micrograms in a clinic, then took 6 micrograms at home, eventually working their way up to 20 micrograms.The participants were asked to avoid potentially risky activities for six hours after dosing and to skip doses after 2 pm to prevent problems with sleep. They used a custom smartphone app to guide them through the study, track their activities on dosing days, and record how they felt at the end of each day.Inside the ketamine therapy boom: Depressed patients say drug has given them another shot at lifeTwo to seven days after taking their last microdose, the researchers visited participants at home for a final check-in. By the end of the eight-week period, two participants dropped out for reasons unrelated to the trial, and one withdrew due to anxiety on dosing days. But for those who completed the study, all of the measures being tracked by researchers showed clear improvements. At the start, the average MADRS score was 23.7. By the end of treatment, it had dropped nearly 60% to 9.6. In fact, nine participants met the criteria for remission. “Patients in this trial experienced a pronounced, long-lasting reduction in depressive symptoms evident from two weeks after the commencement of microdosing until at least the end of the regimen,” the authors wrote. “The reduction of symptoms continued at four weeks of treatment, which stabilized and lasted up to six months after the end of treatment.”The study also found that anxiety scores dropped by more than 50%, while rumination — or the tendency to dwell on negative thoughts — fell by 15%.Participants reported better quality of life across physical, psychological, social and environmental areas, suggesting they were more able to enjoy life and take interest in activities than before the microdosing began. One participant with high baseline anxiety withdrew at the 6 microgram mark, but their symptoms resolved after leaving the study. Researchers also performed echocardiograms, or heart ultrasounds, before and after the study in 15 participants. Four participants continued treatment for another eight weeks, and their hearts were monitored as well.The researchers said their findings suggest that microdosing LSD may have therapeutic potential for depression. However, they stressed that more research is needed to fully understand its effects. A larger trial is already underway to see whether LSD provides greater benefits than a placebo when self-administered at home.Woman, 23, flees NYC after cabbie allegedly sexually assaults her — and is let off hook by DA Bragg: ‘I was so scared’ 'Very shy' teen who leaped to his death from NYC HS was to be punished for stance in ethics class: sourcesFukume - stock.adobe.com
Health Anxiety Depression Lsd Psychedelics Study Says Therapy
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