p|HealthyWomen's Senior Editor/p|p|Jacquelyne Froeber is an award-winning journalist and editor. She’ holds a BA in journalism from Michigan State University.
Jacquelyne Froeber is an award-winning journalist and editor. She’ holds a BA in journalism from Michigan State University. She is the former editor-in-chief of Celebrated Living magazine and has editing and writing experience for print and online publications, including Health magazine, Coastal Living magazine and AARP.
org. Do you remember the scene in “Alice in Wonderland” when Alice nibbles on a mushroom so she doesn’t grow too big or shrink too small? That’s pretty much the thought process behind microdosing. You don’t take enough of the psychedelic drug to experience a real notable change, but the tiny dose may have mental perks, like reducing anxiety andRead: Are Medical Mushrooms Really Magic? >>The increase in curiosity around microdosing psilocybin may be due, in part, to the its decriminalization over the past few years in several states and cities across the U.S. Decriminalization of magic mushrooms, or shrooms, means that there are no criminal penalties for personal use. However, it’s important to note that psilocybin is still illegal on the federal level, even in states where it’s decriminalized. And the lack of regulation can mean whatever product you’re buying could be fake or contain harmful ingredients.Microdosing is taking a very small amount of a psychoactive substance to enhance your mood without the mind-altering side effects. “Microdosing puts too little of the stuff in your brain to produce a psychedelic experience,” Grigsby said. “Some people report that they get a little buzz off of it, and if so, they may have taken slightly more than needed.” When you microdose mushrooms, you take a much smaller dosage than you would if you wanted to hallucinate or “trip.” And people who microdose generally take these doses on a semi-regular basis — two or three days a week.There are different ways to microdose mushrooms. The mushrooms can be chewed up dry or added into a hot tea or a broth/soup. They can also be crushed or put in a coffee grinder and mixed in chocolate or put in gelatin capsules and taken orally.A microdose works the same way as a regular dose, just with different effects. The psilocybin is first converted to, the active ingredient. When it reaches the brain. The psilocin binds to serotonin receptors — especially one called 5-HT2A — which play a role in brain functions like perception and mood. That triggers, on a small scale, a biochemical cascade which is thought to eventually cause reactions at dopamine receptor sites. found that people microdosing psilocybin reported improved mood, feeling more connected to other people and cognitive enhancement, the jury is still out on the “There isn’t any good research on the subject, only observational studies that rely on self-report — no clinical trials or experiments,” Grigsby said. Someshows people reported improved mood, more energy, productivity, creativity and clear thinking, but there’s no control group for comparison. “Statistically, it’s possible to take into consideration people’s expectations, and that can then explain the entire effect. So, it could be a placebo effect.”There is little research on the effects of microdosing mushrooms and no guidelines regarding who shouldn’t try it. That said, someMicrodosing may also not be good for people with a history of psychosis or a family history of psychosis. “Again, we don't know for sure, but if someone withMicrodosing psilocybin is not recommended for people who are pregnant. “Although the dose is very small, and psilocybin is safe and basically non-toxic, like with many drugs, pregnant and lactating women ought not to try microdosing,” Grigsby said.
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