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Metformin’s safety in pregnancy is questioned after studies show it doesn’t benefit offspring, highlighting the need for alternative treatments and better management of gestational diabetes.
These numbers are alarming because excessively high blood sugar levels during pregnancy are associated with negative consequences for mother and child. This increases the risk of affected women developing type 2 diabetes later on and their children have a higher risk of developing metabolic disorders and being overweight.administration when lifestyle changes show no success during the treatment of gestational diabetes.
Treatment involved insulin, metformin, or a placebo, whereby the dosage was based on standard human treatments. The research team collected data on the body weight of the mice, analyzed various metabolic parameters and hormones, and examined molecular signaling pathways in the hypothalamus.
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